What is Robaxin and Where to Buy Robaxin online from US Pharmacy ?

Robaxin (methocarbamol) is a muscle relaxer. It works by blocking nerve impulses (or pain sensations) that are sent to your brain. Methocarbamol is a muscle relaxant that not only reduces tension in the muscles, but also reduces muscle spasms.

Robaxin is used together with rest and physical therapy to treat skeletal muscle conditions such as pain or injury.

Robaxin injection is sometimes used in the treatment of tetanus, (lockjaw) which causes painful tightening of the muscles.

Robaxin contains one active ingredient:  methocarbamol to relax tense back muscles.

Methocarbamol is a muscle relaxant that not only reduces tension in the muscles, but also reduces muscle spasms.  Robaxin can be safely taken in combination with pain relievers, such as Advil.

Along with physical therapy and rest, the drug can help relieve muscle spasms brought on by strains, sprains, and other muscle injuries.

Methocarbamol, which is available only by prescription, comes as a tablet in different strengths—Methocarbamol 500 mg or Methocarbamol 750 mg.

It was first approved by the Food and Drug Administration (FDA) in 1957 under the brand name Robaxin; today, it’s manufactured by Schwarz Pharma. Methocarbamol is also available as a generic drug.

Important Information

You should not use Robaxin if you are allergic to methocarbamol.

Before using Robaxin, tell your doctor if you have myasthenia gravis.

You may need to reduce your dose after the first 2 or 3 days of treatment. Follow your doctor’s instructions regarding the number of tablets you take each day.

Robaxin may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert. Drinking alcohol can increase certain side effects of this medicine.

Because methocarbamol is a central nervous system depressant, it can cause drowsiness and slow down your reaction time.

You should be careful taking this drug if you need to drive, operate machinery, or perform any activity that requires you to be alert.

These effects can increase if you combine methocarbamol with alcohol.

It’s unclear whether methocarbamol is safe to take during pregnancy.

It should be taken only if your doctor feels the risks outweigh the benefits. Methocarbamol should be used with caution if you are breastfeeding.

Methocarbamol is not approved for anyone younger than 16.

Before taking methocarbamol, it’s important to tell your doctor about all your medical conditions, as well as your alcohol use and drug use. Tell your doctor if you have allergies to any medications.

Also tell your doctor if you are pregnant, may become pregnant, or are breastfeeding.

Before taking this medicine

You should not use Robaxin if you are allergic to methocarbamol.

To make sure this medicine is safe for you, tell your doctor if you have:

      • kidney disease;
      • a seizure; or
      • myasthenia gravis.

Methocarbamol may harm an unborn baby. Use effective birth control to prevent pregnancy, and tell your doctor if you become pregnant.

It may not be safe to breastfeed while using this medicine. Ask your doctor about any risk.

Robaxin is not approved for use by anyone younger than 16 years old unless to treat tetanus.

How should I use Robaxin?

Take Robaxin exactly as prescribed by your doctor. Follow all directions on your prescription label and read all medication guides or instruction sheets. This medicine is only part of a complete treatment program that may also include rest, physical therapy, or other pain relief measures.

Robaxin oral is taken by mouth. You may need to reduce your dose after the first 2 or 3 days of treatment. Carefully follow your doctor’s dosing instructions.

Robaxin injection is injected into a muscle or given as an infusion into a vein. A healthcare provider will give you this injection.

The injection is usually given as a single dose before you start taking the oral form.

Tell your caregivers if you feel any burning, pain, or swelling around the IV needle when the medicine is injected.

This medicine can affect the results of certain medical tests. Tell any doctor who treats you that you are using Robaxin.

Store at room temperature away from moisture and heat. Keep the bottle tightly closed when not in use.

Robaxin dosing information

Usual Adult Dose for Muscle Spasm:

Initial Dose: 1500 mg orally 4 times a day
-Doses of 6000 mg per day are generally used for the first 48 to 72 hours
-In severe cases, doses up to 8000 mg per day may be used

Maintenance dose:
500 mg tablets: 1000 mg orally 4 times a day
750 mg Tablets: 750 mg orally every 4 hours OR 1500 mg orally 3 times a day

-For the relief of moderate symptoms: 1 g IV or IM once, then switch to oral
-For relief of severe symptoms or postoperative conditions: 1 g IV or IM every 8 hours
Maximum Dose: 3 g in 24-hours
Maximum Duration: 3 consecutive days; may repeat after a drug-free interval of 48 hours

-Higher doses are recommended in the first 48 to 72 hours of treatment, then doses can usually be reduced to approximately 4000 mg per day.
-Oral tablets should be administered whenever feasible; IV/IM therapy should not be administered for more than 3 consecutive days without a drug-free interval of 48 hours.

Use: As an adjunct to rest and physical therapy for the relief of discomfort associated with acute, painful musculoskeletal conditions.

What is the dosage for methocarbamol-oral?

Musculoskeletal pain in adults:

    • Initially, take three 500 mg tablets by mouth 4 times a day for first 48 to 72 hours, then take 2 tablets by mouth 4 times a day for the maintenance of spasms.
    • If using 750 mg tablets take 2 tablets by mouth 4 times a day for the first 48 to 72 hours, then take 1 tablet by mouth every 4 hours or take 2 tablets by mouth 3 times a day for the maintenance of spasms.
    • The dose for injections is 1 gram intravenously or intramuscularly every 8 hours with a maximum dose of 3 grams per day for 3 days.
      • If needed, the same course may be repeated after a 48 hour drug free interval.

Tetanus spasms:

    • Adults: Inject 1 to 2 grams intravenously every 6 hours as needed with a maximum dose of 24 grams per day.
    • Children: Inject 15 mg/kg intravenously every 6 hours as needed.
      • The total dose should not exceed 1.8 g/m2 for 3 consecutive days.

Take the medicine as soon as you can, but skip the missed dose if it is almost time for your next dose. Do not take two doses at one time.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

Overdose symptoms may include nausea, extreme drowsiness, fainting, seizure, or coma.

What should I avoid while taking Robaxin?

Avoid driving or hazardous activity until you know how this medicine will affect you. Dizziness or drowsiness can cause falls, accidents, or severe injuries.

Drinking alcohol with this medicine can cause side effects.

Robaxin side effects

Get emergency medical help if you have signs of an allergic reaction to Robaxin: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Stop using Robaxin and call your doctor at once if you have:

    • a light-headed feeling, like you might pass out;
    • slow heartbeats;
    • a seizure;
    • jaundice (yellowing of your skin or eyes); or
    • pain, bruising, swelling, or skin changes where the injection was given.
    • headache, dizziness, drowsiness;
    • fever;
    • confusion, problems with memory;
    • nausea, vomiting, upset stomach;
    • blurred vision, double vision;
    • flushing (warmth, redness, or tingly feeling);
    • sleep problems (insomnia); or
    • lack of coordination.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Using Robaxin with other drugs that make you sleepy or slow your breathing can cause dangerous side effects or death. Ask your doctor before using opioid medication, a sleeping pill, a muscle relaxer, or medicine for anxiety or seizures.

Other drugs may interact with methocarbamol, including prescription and over-the-counter medicines, vitamins, and herbal products. Tell your doctor about all your current medicines and any medicine you start or stop using.

Always tell your doctor about all medications you’re taking, including other prescription drugs, over-the-counter drugs, and any vitamins, diet supplements, or herbal remedies.

Any drug that suppresses your central nervous system may interact with methocarbamol. This includes drugs used for seizures, pain, depression, cough and colds, sleep issues, and anxiety.

If you’ve been diagnosed with the disease myasthenia gravis that affects the skeletal muscles, you may not take be able to take methocarbamol.

That’s because some drugs used to treat myasthenia gravis are weakened by methocarbamol.

What are the main differences between Robaxin and Flexeril?


Robaxin, known by its generic name methocarbamol, was released on the market in the 1960s. While its exact mechanism of action is unknown, Robaxin is believed to relieve discomfort through its sedative effects. It does not directly affect muscle contractions.

Robaxin is available as a brand name or generic medication. It comes as an injection as well as a 500 mg or 750 mg oral tablet. Those who are prescribed Robaxin tablets need to take two or three tablets four times per day, initially. Then, one or two tablets three to four times per day or more is recommended.


Flexeril was initially approved by the FDA in the 1970s. It primarily works on the brain stem and spinal cord in the CNS, which helps reduce motor activity. Flexeril is also structurally similar to tricyclic antidepressants and has similar side effects such as dry mouth and sedation.

Flexeril is commonly known by its generic name cyclobenzaprine. Brand-name Flexeril has been discontinued; however, cyclobenzaprine is available in two other brand names: Amrix (extended-release) and Fexmid (immediate-release). The extended-release tablet can be taken once per day.


Robaxin Flexeril
Drug class Muscle relaxant
Antispasmodic agent
Muscle relaxant
Antispasmodic agent
Brand/generic status Brand and generic version available Brand and generic version available
Brand name Flexeril has been discontinued in the US. Other brand names include Amrix and Fexmid.
What is the generic name? Methocarbamol Cyclobenzaprine
What form(s) does the drug come in? Oral tablet
Oral tablet
Oral capsule, extended-release
What is the standard dosage? Initial dosage: 1500 mg 4 times daily
Maintenance dosage: 1000 mg 4 times daily, 1500 mg 3 times daily, or 750 mg every 4 hours
Immediate-release tablets: 5 mg three times daily. Dose may be increased to 10 mg 3 times daily.
Extended-release capsules: 15 mg once daily. Dose may be increased to 30 mg once daily.
How long is the typical treatment? Short-term or long-term treatment as directed by your doctor No more than 2 to 3 weeks
Who typically uses the medication? Adults and young adults ages 16 years or older Adults and young adults ages 15 years or older 

Conditions treated by Robaxin and Flexeril

Robaxin and Flexeril are FDA approved to treat discomfort or muscle spasms from acute musculoskeletal conditions as well as tetanus.

Robaxin or Flexeril are usually prescribed to treat musculoskeletal pain such as neck pain. Both drugs are also often used to treat low back pain, a common problem in adults in the US. Up to 80% of adults experience low back pain at some point in their lives.

Flexeril has also been studied to treat fibromyalgia, a chronic condition characterized by muscle pain all over the body. Those with fibromyalgia may experience widespread muscle pain as well as problems with sleep, fatigue, and mood. According to a meta-analysis of five clinical trials, cyclobenzaprine was found to improve sleep and pain in patients with fibromyalgia over a period of up to 24 weeks.


Condition Robaxin Flexeril
Muscle spasms Yes Yes
Musculoskeletal conditions Yes Yes
Tetanus Yes Yes
Fibromyalgia No Off-label

Is Robaxin or Flexeril more effective?

Robaxin and Flexeril are effective treatments for treating musculoskeletal pain and muscle spasms. The more effective drug is the one that works best for your specific case.

Flexeril is one of the most studied muscle relaxants; thus, it has more supporting evidence for its effectiveness. In a systematic review, it was found that, in general, muscle relaxants are comparable in effectiveness. This review included other muscle relaxants such as metaxalone, baclofen, tizanidine, orphenadrine, and chlorzoxazone.

In a head-to-head trial between methocarbamol and cyclobenzaprine, there was no significant difference in muscle spasms or tenderness. However, patients experienced slightly better improvements in local pain with cyclobenzaprine (48% vs. 40%). Cyclobenzaprine was also found to produce more somnolence or drowsiness (58% vs. 10%).

Cyclobenzaprine has been compared to Valium (diazepam) and Soma (carisoprodol) in clinical trials. Cyclobenzaprine was similarly effective to these drugs for treating acute low back pain.

Consult a healthcare provider for medical advice to find the best treatment options for you. After a complete assessment from a doctor, one drug may be preferred depending on your overall medical history.

Common side effects of Robaxin vs. Flexeril

The most common side effects of Robaxin and Flexeril are drowsiness, dizziness, and headache. Flexeril may be associated with more drowsiness compared to Robaxin. Because of its anticholinergic properties, Flexeril can also cause dry mouth.

Both Robaxin and Flexeril can cause some degree of fatigue or nausea.

More serious side effects include hypersensitivity reactions. These allergic reactions can manifest as trouble breathing, severe rash, and swelling. Seek immediate medical attention if you experience these adverse effects.

  Robaxin Flexeril
Side effect Applicable? Frequency Applicable? Frequency
Drowsiness Yes * not reported Yes 29%
Dizziness Yes * Yes 1%–3%
Headache Yes * Yes 5%
Dry mouth No Yes 21%
Fatigue Yes * Yes 6%
Nausea Yes * Yes 1%–3%

This may not be a complete list. Consult your doctor or pharmacist for possible side effects.
Source: DailyMed (Robaxin), DailyMed (Flexeril)